(Senior) Scientist Primary Pharmacology of the Target Incubator Unit (f/m/d)

If you’re passionate about changing lives for the better, this is the opportunity you’ve been waiting for. In Research & Development, we’re continuously exploring innovative new treatment options to make a stronger, more positive impact on the lives of the patients we serve. You’ll work with talented colleagues in a state-of-the-art Research & Development environment, developing innovative medicines that change the life of patients for the better and help us make progress towards our vision of a world free of pain. Join us today, and discover the difference you can make.

What the job looks like

Each day you’ll enjoy a variety of challenges, such as:

• Independently design, perform and analyze in vitro experiments to generate impactful data to support our pre-clinical assets such as small molecules, biologics or RNA-modulating oligonucleotides.

• Evaluate innovative pain targets, identify tool compounds and assay set ups that allow to address them, including determining their modes of action.

• Represent Primary Pharmacology in cross-disciplinary teams that propose, manage and drive internal therapeutic research projects or external collaborations from academia, biotech or pharma.

• Develop and implement state-of-the-art assays and platforms for target exploration as well as mechanistic evaluation of therapeutic assets.

• Work hands-on in our biology laboratories in Aachen, Germany. Use scientific expertise to guide and develop laboratory technical staff in their assignments and ensure excellent data quality and documentation.

• Foster open and clear communication within the team and across different functions.

What you’ll bring to the table
To make the most of this role and truly thrive, you should have:

• A PhD in in vitro pharmacology, neuroscience, cell biology, biochemistry or related discipline with a minimum of 3 years’ work experience in drug discovery in an industrial setting.

• Experience and proven track record in the development and use of relevant cellular and biochemical assays (for instance binding assays, cellular signaling, Ca++ flux, HTRF-based assays, high content imaging, RT-PCR). Practical knowledge of biophysical methods such as SPR, MST or NMR is an advantage.

• Hands-on experience of cell culture techniques including cell lines, primary cells and/or iPSC-derived models.

• A passion for data quality and excellent data analysis capabilities, including expert knowledge of relevant software and regression models and a quantitative mindset to make optimal use of in vitro data.

• Experience in screening standards and the development of small molecule therapeutics and/or alternative modalities such as biologics or RNA therapeutics.

• A good understanding of human chronic pain disorders is advantageous.

• Excellent organizational and communication skills with a high level of team spirit and pro-activity.

• Ability to challenge the status quo and to embrace change.

What are some of the local benefits

• Hybrid working model

• Bilingual daycare centre “Karlinis“ and holiday activities for employees’ children

• 30 holidays, plus 6-8 bridging days and possibility to convert salary into up to 5 additional holidays

• (E-) Bike leasing and e-charging stations

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”Are you a skilled in vitro pharmacologist with a passion for data-driven research to change the lives of chronic pain patients for the better? We are looking for an experienced scientist to strengthen our Primary Pharmacology team. Apply now and play a pivotal role in designing and executing experiments and contributing to the development of novel therapeutics.” Ramona Schrage, the Hiring Manager