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New Modalities - RNA Therapeutics (m/f/d)

Country:  USA
City:  Boston, MA
Department:  Research & Development
Job ID:  41015


If you’re passionate about changing lives for the better, this is the opportunity you’ve been waiting for. In Research & Development, we’re continuously exploring innovative new treatment options to make a stronger, more positive impact on the lives of the patients we serve. You’ll work with talented colleagues in a state-of-the-art Research & Development environment, developing innovative medicines that change the live of patients for the better and help us make progress towards our vision of a world free of pain. Join us today, and discover the difference you can make.


What the job looks like

Each day you´ll enjoy a variety of challenges, such as:

  • Providing expert input to advance and deliver a project from therapeutic design to successful proof-of-concept clinical trial
  • Working collaboratively within a highly matrixed, entrepreneurial environment with internal colleagues and external CROs to deliver innovative approaches in oligonucleotide therapeutics including but not limited to antisense RNA, RNA editing and mRNA therapeutics
  • Optimizing uptake and trafficking of RNA therapeutics with novel delivery metholds to cell types involved in the pain pathway
  • Leveraging a deep knowledge in mRNA platform development, LNP design and formulation, advanced mRNA characterization, process optimization for discovery and development programs
  • Building an external network of collaborations to gain access to the best scientific thinking around the exploration and development of innovative approaches to next generation therapies for Grünenthal's pan portfolio


What you´ll bring to the table
To make the most of this role and truly thrive, you should have:

  • A collaborative spirit with an interest in discovery and development of novel analgesic therapies for chronic pain disorders
  • Ph.D. with >10 years of pharmaceutical industry experience. Degree emphasis in neuroscience, molecular biology, biochemistry or related field
  • Strong foundational knowledge of RNA biology, biochemistry, structural biology and transcriptional/translational mechanisms of gene expression
  • Experience in the design and understanding of modern synthetic methods used in the solid phase oligonucleotide synthesis, novel nucleoside/nucleotide chemistry, manufacturing and purification of oligonucleotides
  • Fluent English language skills in speaking and writing in addition to good communication skills


About Grünenthal

Grünenthal is a global leader in pain management and related diseases. As a science-based, privately-owned pharmaceutical company, we have a long track record of bringing innovative treatments and state-of-the-art technologies to patients worldwide. Our purpose is to change lives for the better – and innovation is our passion. We are focussing all of our activities and efforts on working towards our vision of a world free of pain.

Grünenthal is headquartered in Aachen, Germany, and has affiliates in 28 countries across Europe, Latin America and the US. Our products are available in more than 100 countries. In 2021, Grünenthal employed around 4,500 people and achieved sales of € 1.5 bn.

Your HR contact:
Claire Sumner

Meet our teams
LinkedIn: Grunenthal Group
Instagram: @grunenthal

Meet our teams
Grunenthal Group

Nearest Major Market: Boston

Apply now »