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Innovative products and services

A leader in pain therapy

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Progress for patients

To improve quality of life in the long term for patients living with pain, you need innovations. And that’s exactly what we work on every day. With more than 20% of our annual revenue, our investment in research and development is way above the industry average. We are constantly striving to create new and improved products – products which are effective against symptoms that have previously been difficult to treat, and which cause fewer side effects.


<40 We have worked in the pain area for more than 40 years so we have the experience and dedication to develop new medicines for pain patients
~240 Our 2015 R&D budget to invest into new projects is about € 240 mn
~600 About 600 colleagues work across all aspects of R&D that are required to take a compound from idea to a medicine
330 We have filed around 330 patent applications filed over the last ten years protecting our novel ideas


Our strong track record in successful pain medication began with the launch of Tramal® in 1977, and continues to this day with our latest products. These include therapeutic agents with innovative mechanisms of action, as well as novel dosage forms for a broad range of pain conditions.

  • Around 60 years ago, Grünenthal was the first West German company to produce and sell penicillin.
  • 1977 saw the market launch of Tramal®, which is still the world’s most commonly prescribed centrally effective pain medication containing just one active ingredient.
  • In 2001, we successfully developed and introduced the first pain relief patch in Europe.
  • With Palexia®/Nycynta® we have developed a new kind of pain medication with an unique pharmacological profile and dual mechanism of action.
  • Our INTAC® technology is a new form of tablet that makes prescription drug abuse significantly more difficult thanks to its high mechanical stability and poor solubility.
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International success – Cross-cultural diversity knows no boundaries

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Grünenthal at a glance - Our innovative products are helping patients all over the world